REV- 2: Calculation of the RT50 for Vaccines

REV-2 : Calculation of the RT 50 for vaccines

REV - 2 evaluates and compares RT 50 values for Brucella vaccines using the Probit model.

For more details : see "Statistical procedures for calculating the residual virulence (Recovery Time 50 -RT50-) of Brucella abortus S19 and Brucella melitensis Rev 1 vaccines in mice: theoretical basis and practical applications." from R. Pouillot*, M.J. Grilló**, J.L. Alabart**, B. Garin-Bastuji*** and J.M. Blasco**, Revue Scientifique et technique de l'OIE, 2003, 22 (3), 1051-1063.

* Agence Française de Sécurité Sanitaire des Aliments, Unité d'Appui Epidémiologique à l'Analyse de Risque, BP19, F-94701 Maison-Alfort Cedex (France).
** Unidad de Sanidad Animal, Servicio Investigación Agroalimentaria, Diputación General de Aragón. Apartado 727. 50080. Zaragoza (Spain).
*** Agence Française de Sécurité Sanitaire des Aliments, Unité des Zoonoses Bactériennes, BP19, F-94701 Maison-Alfort Cedex (France).

Just follow the line ...

1. Complete the table:

NAME : Name of the vaccine for identification purpose
TIME : Point-time of slaughter (by default : 3, 6, 9, 12 weeks)
TREATED : Number of treated mice at each point time of slaughter (by default : 8 animals. Change this number if some animals died during the experiment)
CURED : Number of cleared mice (at each point-time of slaughter, no correction needed if CURED=0 or CURED=TREATED)

Reference			vs	Tested
Name				Name
TIME	TREATED	CURED		TIME	TREATED	CURED
3				3
6				6
9				9
12				12

2. Check this box if you want detailled statistics:

3. Submit your data:

Last update: November 2014. Please send all comments to Bruno Garin-Bastuji or Régis Pouillot